Program

Scheduled Abstracts by Division
Organic Chemistry
Monday AM
OR1
206C
New Frontiers in Peptide Science - joint with BM
Organizer(s) - William Lubell, David Perrin, Andrei Yudin
Chair(s) - William Lubell
08:00
Mechanistic and Structural Studies of Faerocin MK, a Type IIa Bacteriocin Chiorean S, van Belkum MJ, Towle KM, $Vederas JC
08:20
Genetically-encoded Chemically-modified Peptides $*Derda R
09:00
Rational Design of Small Molecule Allosteric Modulators of the Urotensin II Receptor using 1,3,4-benzotriazepin-2-One Turn Mimics Douchez A, Chatenet D, *Lubell WD
09:20
Locked-proline Peptide Chemical Tools to Investigate Kinase and Phosphatase Stereoselectivity $*Etzkorn FA, Zhao S, Fan S, Mayfield JE, Zhang YJ
10:00
 
Coffee Break
10:20
New Methods for Optimal SPPS Efficiency: Higher Purity, Less Solvent, Faster Chemistry $*Collins JM, Singh SK, Porter KA, Karney MJ
10:40
Automated Flow Peptide Synthesis: Toward Amide Bonds at Nature's Pace $*Pentelute BLP
11:20
 
End of Session
OR4
203B
Boron in Modern Organic Synthesis and Catalysis
Organizer(s) - Dennis Hall, Andrei Yudin
Chair(s) - Dennis Hall
08:00
Oxidation of Vinylboronic MIDA Esters: A Source of Useful Building Blocks for Combinatorial Chemistry and Bioconjugation *Lepage ML, $Perrin DM
08:20
Brønsted Acid-catalyzed Reactions of Organoboranes $*Bolshan Y, Harris D, Fisher KM, Baxter M
08:40
Organoboron Catalysts and Reagents for Carbohydrate Chemistry $*Taylor MS
09:20
Boronic Acid Catalysed Activation of Benzylic and Related Alcohols $*McCubbin JA
09:40
Boronic Acid Catalyzed Beckmann Rearrangement of Oximes Mo X, Morgan TDR, $*Hall DG
10:00
 
Coffee Break
10:20
Boron-heteroatom Addition Reactions $*Blum SA
11:00
BCF and Beyond: Modern Advances in Borylation Chemistry $*Melen RL, Wilkins LC, Lawson JR
11:20
 
End of Session
OR8
202B
Recent Advances in the Generation, Utilization and Understanding of Radicals - joint with IN
Organizer(s) - Bas de Bruin, Jean-Philip Lumb
Chair(s) - Jean-Philip Lumb
08:00
Catalysis in Single Electron Steps $*Gansäuer A
08:40
Reactions of Photogenerated Open-shelled Organic Intermediates $*Yoon TP
09:20
Catalytic Amination Using High-spin Persistent Radicals $*Betley T
10:00
 
Coffee Break
10:20
Developing, Understanding and Incorporating Photomediated Transformations in Pharmaceutical Development Schultz DM, *Levesque FL, DiRocco D, Davies I, Campeau LC, Lehnherr D, Reibarkh M, Ji Chen Y-N, Dropinski JF, Sheng H, Sherer E, Wismer MK
10:40
Are Radicals Involved in Base Metal Catalyzed Asymmetric Alkene Hydrogenation? Zhong A, Palmer WN, $*Chirik PJ
11:20
 
End of Session
Monday PM
OR1
206C
New Frontiers in Peptide Science - joint with BM
Organizer(s) - William Lubell, David Perrin, Andrei Yudin
Chair(s) - David Perrin
13:40
Design and Development of a Traceless-multicomponent Reaction on Solid Support for Ppeptide Fragment Ligation and Macrocyclization $*Biron E, Jobin S, Méjean A, Galindo SM, Vezina-Dawod S, Liang X
14:20
"Cyclic Azapeptide Synthesis by A3-Macrocyclization" Zhang J, Ahsanullah, Ohm R, Mulumba M, Ong H, $*Lubell WD
15:00
Searching for Selective Catalytic Reactions in Complex Molecular Environments Miller SJ
15:40
 
Coffee Break
16:00
Bicyclic Octapeptide a-Amanitin: A Novel Approach towards the Total Synthesis *Matinkhoo K, $Perrin DM
16:20
Oxadiazole Grafts in Peptide Macrocycles *Appavoo S, $Yudin AK
16:40
 
IntelliSyn Pharma Research Excellence Award Lecture
16:40
Supramolecular and Peptidic Tools for Probing Epigenetic Methylation Pathways Hof F
17:20
Peptide Compression for Cell and Oral Bioavailability Fairlie DP
18:00
 
End of Session
OR4
203B
Boron in Modern Organic Synthesis and Catalysis
Organizer(s) - Dennis Hall, Andrei Yudin
Chair(s) - Erica Tiong
13:40
Translating New Chemical Space to New Function: The Case of BN/CC Isosterism Liu S-Y
14:20
Inter- and Intramolecular Aryl Insertion Reactions of Borylnitrenes $*Williams FJ
14:40
Synthesis and Application of Aminoboronic Acid Derivatives Diaz DB, Scully CCG, Liew SK, Adachi S, Trinchera P, St. Denis JD, $*Yudin AK
15:00
Ambient Decarboxylative Cross-coupling Reactions Enabled by Oxidative Copper Catalysis $*Lundgren RJ
15:40
 
Coffee Break
16:00
 
R.U. Lemieux Award Lecture
16:00
N-heterocyclic Carbenes as Supporting Ligands for Borenium-based Catalysts and on Metal Surfaces $*Crudden CM
16:40
Application of Boron to Overcome the Intrinsic Antibiotic Resistance of the Bio-threat Pathogen Burkholderia Pseudomallei *Perry MA, $Alley MKR
17:20
Boron Hydrides and Fluorides Supported by BAC Carbenes $*Speed AWH
17:40
 
End of Session
OR8
202B
Recent Advances in the Generation, Utilization and Understanding of Radicals - joint with IN
Organizer(s) - Bas de Bruin, Jean-Philip Lumb
Chair(s) - Jean-Philip Lumb
13:40
Radical Cascade Reactions by Electron Catalysis Studer A
14:20
Radicals Enable Charge Transport in Metal-organic Frameworks *Dinca M, Sheberla D, Campbell MG, Dou JH
15:00
Free Radicals in Commercial Oxidation of p-Xylene to Terephthalic Acid Adamian VA
15:40
 
Coffee Break
16:00
The Quest for Stable Oxyallyl Derivatives : Air-persistent Radical Cations Regnier V, Planet Y, Molton F, Philouze C, $*Martin D
16:20
Proton-coupled Electron Transfer in Organic Synthesis $*Knowles R
17:00
Radical Relay Strategies for Selective C-H Oxidation Stahl SS
17:40
 
End of Session
Tuesday AM
OR1
206C
New Frontiers in Peptide Science - joint with BM
Organizer(s) - William Lubell, David Perrin, Andrei Yudin
Chair(s) - William Lubell
08:00
Resolution of rac-a-allylalanine via Continuous Preferential Crystallization (CPC) Patel A, $Hein JE
08:20
Stapled Peptides that Stabilize the Hyaluronan Binding Domains of the Receptor for Hyaluronan Mediated Motility (RHAMM) Rodrigues E, Peart T, Ma J, Toleg C, Turley E, $*Luyt LG
08:40
Targeting the Prostaglandin F2a Receptor to Delay Preterm Birth Mohammadpour F, *Lubell WD
09:00
Silica Grafted Basic Amino Acids as Efficient Catalysts for Chemical Fixation of Carbon Dioxide into Cyclic Carbonates under Metal-free and Halide-free Conditions Heidari Y, Hajipour AR, Kozehgary GR
09:20
Boroscan - An Enabling Technology for Discovery of Boron-containing Therapeutics $*Yudin AK
10:00
 
Coffee Break
10:20
MW Lecture on Late Breaking Peptide Developments $*Perrin DM
10:40
The Development of Cyclic Peptides as RHAMM Mimics for Blocking Inflammation Hauser-Kawaguchi A, Peart T, Tolg C, Turley E, $*Luyt LG
11:00
Impact of Homochirality on Peptide Self-assembly Basak S, $Kraatz B
11:20
Transforming Peptides into PET Imaging Agents Through User-friendly 18F-labeling $*Perrin DM, Lin K-S, Benard F, Lepage M, Roxin A, Huh S, Zhang C, Zhang Z, Dude I, Pan J
12:00
 
End of Session
OR2
205B
A Century of Organic Synthesis in Australia and Canada
Organizer(s) - Louis Barriault, Robert Britton, Mike Kerr
Chair(s) - Louis Barriault
08:00
Unveiling the Umpolung Reactivity of Carbonyl Compounds Dai X-J, Wang H, $*Li C-J
08:20
Development of New Metal-free Photochemical Methodologies Using Continuous Flow Chemistry for the Synthesis of Carbazoles. Parisien-Collette S, Cruché C, $*Collins SK
08:40
Catalytic Undirected Intermolecular C-H Functionalization of Arenes with 3-Diazofuran-2,4-dione: Synthesis of 3-Aryl Tetronic Acids and Pulvinic Acids $*Pansare SV, Manchoju A
09:00
Chemoenzymatic Dihydroxylation in the Synthesis of Natural Products. Approach to (-)-Tetrodotoxin Rycek L, Trant JF, Froese J, Murphy B, $*Hudlicky T
09:20
The Canadian Front in Synthetic Organic Chemistry. A Mari usque ad Mare (D'un ocean a l'autre) Snieckus V
10:00
 
Coffee Break
10:20
The total synthesis of Phomolides G and H and their structural revisions $*McNulty J, McLeod D
10:40
Ley-Griffith Oxidation (TPAP): Selectivity Modulation, Mechanistic Understanding, and New Directions $*Williams CM
11:20
Synthetic Studies on Heterocyclic Natural Products $*Ciufolini MA
12:00
 
End of Session
OR6
203B
Transition Metal Catalysis for Organic Synthesis
Organizer(s) - Stephen Newman, Sophie Rousseaux
Chair(s) - Stephen Newman
08:00
C-H Activation at High Valent Nickel Chong E, $*Sanford MS
08:20
Copper-catalyzed Vinylation of Nitrogenated Species $*Daoust B, Gagnon A, Ricard S, Casault P, Gilbert N, Ladouceur F
08:40
C-H Functionalization Applied to the Efficient Synthesis and Elaboration of Heterocycles $*Ellman JA
09:20
New Classes of Transition Metal Catalyzed Bond Forming Reactions Powered by CO $*Arndtsen BA
10:00
 
Coffee Break
10:20
A Novel Pd-Catalyzed "Asymmetric C-N Coupling" for the Manufacture of Elbasvir/Ruzasvir *Yin J
11:00
PAd-DalPhos/Nickel-catalysed C-N Cross-coupling Catalysis: Reaction Development and Mechanistic Investigations Lavoie CM, MacQueen PM, Johnson E, $*Stradiotto M
11:20
The Direct Radical Functionalization of Alcohols Using Cobalt Photocatalysis $Martin DBC, Chambers DR, Sodogar E
11:40
Toward an Enantioselective Intramolecular C-H Alkenylation of Cyclopropane Derivatives $*Charette AB, Ladd CL
12:00
 
End of Session
Tuesday PM
OR2
205B
A Century of Organic Synthesis in Australia and Canada
Organizer(s) - Louis Barriault, Robert Britton, Mike Kerr
Chair(s) - Rob Britton
13:40
General Approach toward Aspidospermatan-type Alkaloids $*Bélanger G, Hauduc C
14:00
Biomimetic Synthesis of Meroterpenoid Natural Products George JH
14:40
A Mild Photo-mediated Methylation and Hydroxymethylation of Heteroarenes and Oxidation of Ethers McCallum T, Pitre SP, Morin M, Scaiano JC, Barriault L
15:00
Stereoselective Total Synthesis of Alkaloids and towards a Functional Protecting Group Approach. Maertens G, Deruer E, Coulibali S, Beaulieu MA, Jacquemot G, $*Canesi S
15:40
 
Coffee Break
16:00
Synthesis of Cyclopropylamines via Unusual Zinc-homoenolate Reactivity $*Rousseaux S
16:20
Synthesis and Catalysis with Branched C=C Bond Rich Systems Sherburn MS
17:00
Development of New Cyclopropanation Reactions in Batch and in Flow to Access Polysubstituted Cyclopropanes $*Charette AB
17:40
 
End of Session
OR6
203B
Transition Metal Catalysis for Organic Synthesis
Organizer(s) - Stephen Newman, Sophie Rousseaux
Chair(s) - Stephen Newman
14:00
New Allylic and Homoallylic Cross-coupling Reactions for the Asymmetric Construction of Acyclic Ternary and Quaternary Carbon Stereocenters *Evans PA
14:40
C-H Functionalization in Pharmaceutical Applications $*Malik HA
15:20
Designing Pd-NHC Complexes to Provide Selective Monoarylation $*Organ MG, Lombardi C, Day J, Chandrasoma N, Sharif S, Rucker R, Khadra A
15:40
 
Coffee Break
16:00
Controlling Catalysis with Visible Light $*Rovis T
16:40
Gold(III) Intermediates in Catalysis of Organic Reactions $*Hashmi ASK
17:00
Chirality in Coupling Reactions: Stereoretentive Suzuki-Miyaura Cross-couplings and the Development of New Electrophiles for Cross-coupling Chemistry $*Crudden CM
17:20
Rh/Pd Dual-metal Catalyzed Synthesis of Pyridobenzazepines Lam H, Tsoung J, *Lautens M
17:40
Direct Access to Conjugated Trienes by Ru(0)-catalyzed Coupling of Internal Alkynes with Conjugated Dienes $*Hirano M, Kiyota S, In S, Saito R, Komine N
18:00
 
End of Session
OR9
201F
Functional Organic Pi Systems: Synthesis, Theory and Applications - joint with MT
Organizer(s) - Graham Bodwell, Rik Tykwinski
Chair(s) - Rik Tykwinski
13:40
Adventures of an sp3 Chemist in the sp2 World $*Schreiner PR
14:20
Phosphangulene and Phriends: Bowl-shaped Molecules and their Co-crystallizations with Fullerenes Heskia A, Maris T, Wuest JD
14:40
Nanohoops as New Architectures in Materials Design $*Jasti R
15:20
Synthetic Studies on [10]-Annulenes Blaquiere C, $*Gravel M
15:40
 
Coffee Break
16:00
Polycyclic Heteroaromatic Compounds: From Chemical Synthesis to Molecular Materials $*Kivala M
16:40
Regioisomeric Effects of Donor-acceptor Pyrene Based Chromophores $*Sutherland TC
17:00
[n](2,9)Peropyrenophanes MacKinnon MR, Kubo T, $*Bodwell GJ
17:20
Sulfonamide-based Pi-conjugated Systems for Organic Electronics $*Chan JM
17:40
 
End of Session
OR10
206E
Fluorinated Molecules: Syntheses, Analyses, and Applications - joint with BM
Organizer(s) - Jean-François Paquin, Glenn Sammis
Chair(s) - Jean-François Paquin
13:40
Metal Catalyzed Strategies to Trifluoromethyl-containing Molecules $*Lautens M, Johnson T
14:00
Development of a F-18 Labeled Pyridine Analog of Losartan for Translational PET Imaging of AT1 Receptors $*DaSilva JN
14:20
Recent Developments in the Preparation of Monofluoroalkenes from 3-Fluoro-3-halopropenes Hamel J-D, Cloutier M, Drouin M, $*Paquin J-F
14:40
Development of an 18F-labelled Derivative of the FFA1-agonist TAK875 Dornan MH, Poitout V, $*DaSilva JN
15:00
Fluoroalkyl Groups and Sulfur or Selenium Associations: New Opportunities in Molecules Design $*Billard T
15:40
 
Coffee Break
16:00
Fluoroform-derived CuCF3 for Trifluoromethylation and Hydrotrifluoromethylation of Alkynes $*Tsui GC, He L
16:20
Asymmetric Fluorohydrin Synthesis: A Scaffold for Accessing Fluorinated Biologically Relevant Molecules Meanwell M, Ren W, Bergeron-Brlek M, Movahedi S, Dudding T, $*Britton R
16:40
Generation and Capture of Difluorocarbenium Ion By Silylium Cation-phosphine Frustrated Lewis Pairs and Conversion of a,a,a-Trifluorotoluene to a,a-Difluorotoluene Mallov I, Ruddy AJ, Zhu H, Grimme S, $*Stephan DW
17:00
Synthesis and Biological Evaluation of Mono- and Poly-fluorinated Carbohydrates $*Giguère D
17:20
Unusual Properties of Selectively Fluorinated Aliphatic Rings O'Hagan D
18:00
 
End of Session
Wednesday AM
OR2
205B
A Century of Organic Synthesis in Australia and Canada
Organizer(s) - Louis Barriault, Robert Britton, Mike Kerr
Chair(s) - Michael Kerr
08:00
Chemoenzymatic Total Synthesis of the Hydroxylated Cyclohexenone Carboxylic Acid Moiety of Xylosmin Ghavre M, Froese J, Murphy B, Simionescu R, $*Hudlicky T
08:20
Synthesis of Previously Inaccessible Electron-poor Allylboronates and their Application in the Heterocycle Synthesis Shao W, Kaldas SJ, Yudin AK
08:40
Utility of Iron Nanoparticles and a Solution-phase Iron Species for the N-demethylation of Alkaloids $*Singer RD, Awalt JK, Lam R, Kellam B, Graham B, Scammells PJ
09:00
Revisiting the Mechanism of Thiele's Ester and Applications of its Derivatives Chen J, Kilpatrick B, Moffitt MG, Oliver AG, Burns F, $Wulff JE
09:20
Gold Catalysis for Organic Synthesis $Gagosz F
10:00
 
Coffee Break
10:20
The Total Synthesis of Virosaine A $*Gleason JL, Hughes JME
10:40
 
Alfred Bader Award Lecture
10:40
Synthesis of Bioactive Macrocycles $*Yudin AK
11:20
 
End of Session
OR5
201C
Recent Advances in Metal-free Transformations
Organizer(s) - André Beauchemin, Yuri Bolshan
Chair(s) - Yuri Bolshan
08:00
Metal-free Intermolecular Cyclopropanation of Alkenes Using Iodonium Ylides Tao J, Estrada CD, $*Murphy GK
08:20
A Solution to the ProTide Synthesis Problem: Adventures in Asymmetric Nucleoside Phosphorylation *Campeau L-C
09:00
Utilizing Divergent Photocyclization/1,4-Sigmatropic Rearrangements for Sesquiterpenoid Synthesis $*Derksen DJ
09:20
Boronic Acid Catalysis for Direct Activation and Transformations of Hydroxyl Functional Groups $*Hall DG, Mo X, Morgan TDR, Verdelet T
10:00
 
Coffee Break
10:20
Metal-free Cycloetherification by in Situ Generated P-Stereogenic Diazanium Intermediates: A Convergent Synthesis of Enantiomerically Pure Dihydrobenzooxaphospholes Li S-G, Han ZS, Viereck P, Lee H, Kurouski D, Senanayake CH, *Tsantrizos YS
10:40
Iodine-based Reagents: A Purple Future for Additions and Rearrangements Wirth T
11:20
 
End of Session
OR6
203B
Transition Metal Catalysis for Organic Synthesis
Organizer(s) - Stephen Newman, Sophie Rousseaux
Chair(s) - Sophie Rousseaux
08:00
Novel Ester Metathesis Reaction Catalyzed by Organometallic Ruthenium Complexes: Application to Transfer Hydrogenation of Esters $*Khaskin E, Dubey A
08:20
Decarboxylative and Desulfinative Cross-coupling Reactions as a Veratile Synthetic Tool Forgione P
08:40
Highly Regioselective Gold-Catalyzed Formal Hydration of Propargylic gem-Difluorides as a Synthetic Equivalent to the Selective Deoxofluorination of 1,3-Diketones Hamel J-D, Hayashi T, Cloutier M, Savoie PR, Beaudoin M, $*Paquin J-F
09:00
in-situ Tantalum-catalysed Hydroaminoalkylation: Accessing Novel Substrates and Selective Reactivity via Ligand Tunability *DiPucchio RC, Rosca SC, $Schafer LL
09:20
Application of Non-precious Metals Catalysis in the Synthesis of Pharmaceuticals Monfette S
10:00
 
Coffee Break
10:20
Z-Selective Cross-coupling of Allylic Carbonates and a-Diazo Esters $*Lundgren RJ
11:00
Simplifying Earth-abundant Metal Catalysis Thomas SP
11:20
 
End of Session
OR7
206F
Advances in Heterocycle Synthesis
Organizer(s) - Louis-Charles Campeau, Ernest Lee
Chair(s) - Ernest Lee, Louis-Charles Campeau
08:00
Development and Application of Flow Chemistry Methodologies in Heterocycle Synthesis $*Tranmer GK, Fang Y
08:20
Direct Functionalization of Pyridines with Cyclopropanol Derived Radicals: The Cyclopropanol Minisci Reaction $*Orellana A, Nikolaev A, Zhang M
08:40
Development of the Cu(I)-catalyzed [3+2] Asymmetric Cycloaddition Process for the Manufacture of Idasanutlin Fishlock D
09:20
Selective Functionalization of Pyridines and Diazines via Heterocyclic Phosphonium Salts $*McNally A
10:00
 
Coffee Break
10:20
Utilizing a Versatile N-Silylenamine Intermediate Towards a Modular Synthesis of Poly-substituted Pyridines Lui EKJ, $*Schafer LL
10:40
Rapid Synthesis of Stereochemically Rich Heterocycles and New Methods for the Direct Functionalization of Heterobenzylic C-H Bonds Britton RA
11:20
 
End of Session
OR9
201F
Functional Organic Pi Systems: Synthesis, Theory and Applications - joint with MT
Organizer(s) - Graham Bodwell, Rik Tykwinski
Chair(s) - Graham Bodwell
08:00
Optically Switching Charge and Energy Transfer Processes in Pi Conjugated Chromophores: Molecules to Devices $*Frank NL, Kurimoto A, Paquette MP
08:40
Alkynyl PDI Derivatives as a Versatile Platform for Diverse Functional Materials for Organic Electronics Cann JR, $*Welch GC
09:00
Phenylacetylene Scaffolding as Receptors for Anions: Synthesis, Supramolecular Chemistry and Emerging Applications $*Haley MM
09:40
Redox Controlled Supramolecular Chemistry Based on Viologen Architectures *Weiss J, $Wytko J, Berville M
10:00
 
Coffee Break
10:20
Boron Subphthalocyanines and Boron Subnaphthalocyanines: Very Versatile Materials with Robust Chemistry and High Stability for Applications in Organic Photovoltaics/Solar Cells $*Bender TP
11:00
Electronic and Magnetic Interactions between Porphyrins $Ruppert R
11:20
 
End of Session
OR10
206E
Fluorinated Molecules: Syntheses, Analyses, and Applications - joint with BM
Organizer(s) - Jean-François Paquin, Glenn Sammis
Chair(s) - Glenn Sammis
08:00
Stability and Polarity of the Insertion Complexes of Fluorinated Molecules in Ion-pairs $*Naumkin FY, Kerr S
08:20
Optimized Radiofluorination of DFH17 Using Aluminum-fluoride (Al18F) $Alonso Martinez LM, Harel F, Nguyen QT, Letourneau M, D'Oliviera-Sousa C, Meloche B, Fournier A, Dupuis J, *DaSilva JN
08:40
New Synthesis of Monofluoroalkenes Drouin M, Tremblay S, $Paquin J-F
09:00
New Fluorination Reactions of p-(Difluoroiodo)toluene $*Murphy GK, Zhao Z, Kulkarni KG, Miokovic B, Sauder M, Sinclair GS, Tran R, Tao J, Shi J, Racicot L
09:20
One-step, Late Stage 18F-labeling of Peptides and Small Molecules for PET Imaging Cancer $*Perrin DM, Lin KS, Benard F, Lepage M, Roxin A, Zhang Z, Zhang Z, Huh S, Dude I, Liu Z
09:40
Shedding Light on Trk Neurotrophin Receptors with PET Neuroimaging: A 6 year journey Schirrmacher RS, $Bernard-Gauthier VB
10:00
 
Coffee Break
10:20
Biosynthesis of Fluorometabolites and the Perplexing Case of a Missing Molecule Zechel DL
10:40
Importance of Fluorine in Agrochemistry : Example of the Mitochondrial Respiration Inhibitors Fungicides $*Vors J-P
11:20
 
End of Session
Wednesday PM
OR2
205B
A Century of Organic Synthesis in Australia and Canada
Organizer(s) - Louis Barriault, Robert Britton, Mike Kerr
Chair(s) - Michael Sherburn
13:40
Driving Synthesis by Oxidation $Lumb JP
14:20
Recent Adventures in Total Synthesis $*Rizzacasa MA
15:00
New Chemistry for the Generation and Synthetic Exploitation of Strained, Short-lived Cyclic Allenes $*West FG
15:40
 
Coffee Break
16:00
Towards the Total Synthesis of Bruceantin Using a Radical Cyclization Cascade Labelle A, *Spino C
16:20
Catalysis with N-heterocyclic Carbenes via Unusual Reactive Intermediates $*Lupton DW
17:00
Recent Advances in Carbo- and Hydrohalogenation Reactions via Metal Catalysis $*Lautens M
17:40
 
End of Session
OR5
201C
Recent Advances in Metal-free Transformations
Organizer(s) - André Beauchemin, Yuri Bolshan
Chair(s) - Alex WH Speed, Darren J Derksen
13:40
Silatrane: A Versatile and User-friendly Atom-transfer Reagent $*Adler MJ
14:00
Development of a Metal-free Amine Oxidation Method Utilizing DEAD Chemistry $*Davis RL
14:20
Development of Diazepane Carboxylates as Organocatalysts for the Cope Rearrangement, Diels-Alder and Polyene Cyclization $*Gleason JL
14:40
Rationalization of Enantioselectivity in Chiral Phosphoric Acid-catalyzed Reactions of sp3 Electrophiles Using DFT Calculations Champagne PA, *Houk KN
15:00
Exploiting Reversible Covalent Interactions of Boron Compounds in Catalysis $*Taylor MS
15:40
 
Coffee Break
16:00
Metal-free Synthesis of Chiral Building Blocks and Medium Rings $*Sun J
16:40
Application of an Alternative Route to Access N-Heterocyclic Carbene Triazolium Salts: Exploration of the Counter Ion Effect Langdon SM, $*Gravel M
17:00
Sustainable Catalysis - Concepts and Applications *Rueping M
17:40
Enantioselective Metal-free Approach to 5-(1-Hydroxyalkyl) Butenolide Natural Products: Synthesis of (-)-Muricatacin and (-)-L-Factor Cooze C, Manchoju A, $*Pansare SV
18:00
 
End of Session
OR7
206F
Advances in Heterocycle Synthesis
Organizer(s) - Louis-Charles Campeau, Ernest Lee
Chair(s) - Louis-Charles Campeau, Ernest Lee
13:40
Enantioselective Synthesis of Heterocycles from Carbon-carbon Multiple Bonds $*Toste FD
14:20
Process Development of PI3Kd Inhibitor GS-9901 Bykowski D
15:00
Azomethine Ylide Cycloaddition Strategies for Dendrobium Alkaloids Williams BM, $Trauner D
15:20
Photocatalysis Inspired via the Synthesis of Heterocycles $*Collins SK
15:40
 
Coffee Break
16:00
Synthesis of Complex Phenols Enabled by Rationally-designed Hydroxide Surrogates *Maloney K, Fier P
16:40
O-Substituted Isocyanates: A Versatile Tool for the Synthesis of Heterocycles Polat D, Ivanovich RA, *Beauchemin AM
17:00
A Catalytic Aerobic Coupling of Phenols and Amines for the Synthesis of Heterocycles $*Lumb JP, Esguerra KVN, Xu W
17:20
Photocatalytic Synthesis of Enantioenriched Heterocycles $*Yoon TP
18:00
 
End of Session
OR9
201F
Functional Organic Pi Systems: Synthesis, Theory and Applications - joint with MT
Organizer(s) - Graham Bodwell, Rik Tykwinski
Chair(s) - Michael Haley
13:40
A Multicomponent Coupling Approach to Conjugated Polymer Synthesis $*Arndtsen BA
14:20
Synthesis and Properties of Electron Accepting Star-shaped Phosphaviologen Oligomers Striepe LJ, Vespa M, $*Baumgartner T
14:40
Dendritic Phenylene Vinylene Oligomers with An Anthraquinodimethane Core: Synthesis, Photochemical Reactivity, and Application in Chemical Sensing *Zhao Y, $Khadem M, Shahrokhi F, Wang C
15:20
The Synthesis of Reactive Monomers for pi-Conjugated 2D Polymers Abdi OK, *Malakalapalli RR, $Perepichka DF
15:40
 
Coffee Break
16:00
Photochemical Synthesis of Heterocycles-containing Graphene Nanoribbons $*Morin JF, Miao D, Daigle M
16:40
Alkyne Benzannulations to Rapidly Extend p-Conjugation: Synthesis and Study of Contorted and Chiral Polycyclic Aromatics $*Chalifoux WA
17:00
Robust Synthesis of F-BODIPYs Beh MHR, Douglas KIB, House KTE, Murphy AC, Sinclair JST, $*Thomspon A
17:20
Tied Together: The Marriage of Pyridine and Nonplanar PAHs Ghods P, $*Bodwell GJ
17:40
 
End of Session
ORG1
206B
General Session 1
Organizer(s) - Eric Fillion
Chair(s) - Eric Fillion
13:40
 
Canadian Journal of Chemistry Best Paper Award Lecture
13:40
Computational Enzymology: Elucidating the Role of Enzyme Active Sites and their Residues In Ligand Binding, Oxidative Protection, and Catalysis $*Gauld JW
14:20
Development of an Easily Accessable, In-situ Generated Regio- and Diastereoselective Hydroaminoalkylation Catalyst Edwards P, $*Schafer L
14:40
Palladium-catalyzed Decarboxylative and Desulfinative Cross-coupling of Diaryliodonium Salts Taç F, Mangel D, Babity S, Lalonde S, $*Forgione P
15:00
New Routes to Families of NHC-Gold(I) Catalysts $*Hashmi ASK
15:20
Palladium-catalyzed Carbonylative Synthesis of Pyrroles and Beta-lactams Martin Torres G, $Arndtsen BA
15:40
 
Coffee Break
16:00
Tackling Challenging Amine Nucleophiles in Nickel-catalyzed C-N Cross-coupling through Tailored Ligand Design Tassone JP, MacQueen PM, Lavoie CM, $*Stradiotto M
16:20
Enantioselective Iron and Copper Catalyzed Carbenoid Insertion Reactions into Si-H Bonds Keipour H, *Ollevier T
16:40
Applications of Aromatic Sulfinates Derivatives in Synthesis - Using Pyridine as Both a Protecting Group and a Directing Group for Pd-catalyzed ortho-Halogenation Chen F, $*Forgione P
17:00
Reactivity of New NCN-type Pincer Complexes of Ni(III) Cloutier JP, Zamani F, Zargarian D, Canac Y
17:20
Nickel Catalyzed Amination of Phenol-derived Electrophiles MacQueen PM, $*Stradiotto M
17:40
Rhodium-catalyzed Enantioselective Synthesis of 3,3-disubstituted Oxindoles Jang YJ, Larin E, $*Lautens M
18:00
 
End of Session
ORP
Hall C
Poster Session
From 17:40 until 19:30
17:40
A Cross-coupling Approach to Amide Bonds Formation $Ben Halima T, *Newman S
17:40
TiO2@Pd Nanoparticles as Reusable Catalysts in the Synthesis of N-aryl Sulfonamides Under Mild Reaction Conditions $*Khalaj M, Ghazanfarpour-Darjani M
17:40
Isolation, Charaterization of Alkaloids from Alchorea cordifolia Okoyeagu A, *Mac-Kalunta M
17:40
Immobilization of Palladium (0) Complexes on Triethanolamine Functionalized Coreshell Magnetic Nanoparticles: As a Magnetically Separable and Stable Recyclable High-performance Catalyst for Suzuki-Miyaura Cross-coupling Reactions Pirhayati M, *Veisi H, $Kakanejadifard A
17:40
Sulfur Hexafluoride Reduction by Organic Super Electron Donors *Lebedev Y, Nikolaienko P, $Rueping M
17:40
The Use of Cucurbiturils in Pharmaceutical Sciences $*Wang R, Li S, Yang X, Yin H, Huang Q
17:40
Pushing the Limit on Regioselective Deprotonation of Trialkylphosphine-derived Phosphonium Salts Directed by Cyclic Acetal Protecting Groups *Hurem D, McLeod D, Narayanappa A, $McNulty J
17:40
A Highly Efficient Method for Photocyclization of Bis(diphenylmethylene)dihydroanthracenes $Wang C, *Zhao Y
17:40
Automating Chiral Auxiliary Recycling Sullivan RJ, *Newman SG
17:40
Highly Chemo/Regioselective Organocatalyzed Morita-Baylis-Hillman versus Aldol or Aldol Condensation Reactions of Cyclic Ketones $*Akbarzadeh E
17:40
Magnetite Nanoparticles Coated with Tannic Acid as a Reductant and Stabilizer Sorbent for Palladium Ions: Synthetic application of Fe3O4@TA-Pd NPs as Magnetically Separable and Reusable Nanocatalyst for Reduction of 4-nitrophenol and Suzuki Reactions Pirhayati M, *Veisi H
17:40
Contributions of the Single-molecule Techniques to the Organic Tool-Kit: Click Chemistry as a Proof of Concept Lanterna AE, Wang B, $Scaiano JC
17:40
Functionalization of Pentacene-5,7,12,14-tetraone with Enediyne and Dithiafulvene Groups Younes E, *Zhao Y
17:40
One Step Transformation of Coenzyme A into Analogues by Transamidation Sanichar R, $*Vederas JC
17:40
A New Facile and Efficient Synthesis of 2-((5-aryl-1, 3, 4-oxadiazol-2-yl) Methoxy)-3-methyl Quinoxaline and 2-methyl Quinoxaline-3yl- 5-aryl-2H-tetrazole 2-carboxylate Derivatives $*Maringanti T
17:40
Synthesis and Characterization of Dendritic Oligo(phenylene vinylene)s Shahrokhi F, *Zhao Y
17:40
Total Synthesis of Isoprekinamycin and Prefluostatin via a Double Directed Remote Metalation (DreM) Cyclisation Hurst TE, Patel J, Ziebenhaus C, Kitching MO, $*Snieckus V
17:40
Selective Recognitions of Cis and Trans Isomers of Substituted Cyclohexylamines and Cyclohexylmethanols by Cucurbit[7]uril $*Macartney DH, Katz S, Miao S
17:40
Photochemical Synthesis of Alkynyl Sulfides Using Continuous-flow Santandrea J, Minozzi C, Cruché C, $*Collins SK
17:40
An Asymmetric Iminium-catalyzed Polyene Cyclization Plamondon SJ, Kaldre D, Häggman NO, $*Gleason JL
17:40
A Comparative Study of Solvent-free and Highly Efficient Pinene Hydrogenation over Pd on Carbon, Alumina, and Silica Supports $*Touaibia M, Selka A, Levesque N A, Foucher D, Clarisse O, Chemat F
17:40
Automated Reaction Progress Analysis: A Rapid and Robust Method for Elucidating Catalyst Monopoly Chung R, $*Hein JE
17:40
Solvent Effects on the Stereoselectivity of Aprotic Glycosylations Sadraei S, Ahmad SA, $*Trant JF
17:40
Total Synthesis of the Natural Product (+)-trans-Dihydronarciclasine via an Asymmetric Organocatalytic [3+3]-Cycloaddition and discovery of its potent Antiflaviviral (Zika) Activity *Revu O, Zepeda-Velázquez C, Nielsen AJ, $McNulty J, Yolken RH, Jones-Brando L
17:40
Chiral Catalysis Mediated by Diazaphospholenes Adams MR, $*Speed AWH
17:40
Carbohydrate and Peptide Chemistry: Bridging Biology, Synthetic Chemistry, and Computational Chemistry $*Trant JF
17:40
Discovery of [18F]JNJ-64413739, a PET Ligand for P2X7 Receptor Imaging Chen G, Szardenings AK, Zhang W, Xia C, Berdyyeva T, Huang C, Bhattacharya A, Lord B, Letavic M, Kolb HC
17:40
Experimental and Computational Studies on the Mechanism of the Pd-catalyzed Hydrohalogenation of 1,6-Enynes Petrone DA, Franzoni I, Ye J, Rodriguez JF, Poblador-Bahamonde AI, $*Lautens M
17:40
Synthesis of P-chiral Dihydrobenzooxaphosphole Ligands and their Applications in Asymmetric Catalysis Viereck P, *Li S, Han Z, Lee H, Kurouski D, Senanayake C, $Tsantrizos Y
17:40
Simple and Clean Photo-induced Methylation of Heteroarenes with MeOH Liu W, *Li C-J
17:40
The [5 + 1 + 2 + 1] Rhodium-Catalyzed Cycloaddition Reaction: A Combined DFT and Spectroscopic Study Mbaezue II, $*Ylijoki KEO
17:40
Innovative One-pot Syntheses of Benzoquinone and Benzoquinoneimine Rings Driven by Oxidation $*Odens HH, Odens Jr. HH
17:40
C-H Activation/Borylation of Amide Directed Aromatics Using Ruthenium Catalyst Gupta S, *Snieckus V, Yang J, Zhao Y
17:40
Supramolecular Control of p/n Bulk Heterojunctions Using Complementary Hydrogen Bonding Yee N, *Black HT, $Perepichka DF
17:40
Bent Bond (t) and the Antiperiplanar Hypothesis. A Novel Approach in the Comprehension of Glycosides Reactivity at the Anomeric Center Parent J-F, $Deslongchamps P
17:40
Formal Cycloadditions as an Expeditious Access to Produce Dihydrofuranoindoline and Arylated (Cyclopropane or Aziridine) Cores $Deruer E, Coulibali S, *Canesi S
17:40
Synthesis and Applications of 17O,18O & 2H Labelled (+)-Disparlure, and Their Analogues Pinnelli G, Hillier KN, Lance DR, $*Plettner E
17:40
Synthesis of Biotin-functionalized Biguanide for the Identification of the Tumor Growth Inhibition Mechanism of Metformin Mohebali F, Rowell M, Febeyre G, *Schmitzer A
17:40
Alanine Scan of Daptomycin Barnawi G, $*Taylor SD
17:40
Short Synthesis of Pymetrozine Analogues Using In Situ-generated N-substituted Isocyanates Dahab MA, *Derasp JS, $Beauchemin AB
17:40
A Directed ortho Metalation Approach to Unusually Substituted Indazoles Cullen FJ, Melanson JA, Wang S, $*Snieckus V
17:40
Pressure-controlled Conformational Tuning in Molecular Wires *Wiebe H, Louwerse M, $Weinberg N
17:40
Copper-catalyzed Intramolecular N-halovinylation of Amides and Carbamates Gilbert N, *Daoust B
17:40
Experimental and Theoretical Investigation on the Lithiation of 2,4-Lutidine Singh A, $*Dhau J
17:40
Synthesis of Functionalized bis-Bispidine Macrocycles and their Self-assembly Directed by Weak Long-range C-HàO Hydrogen Bonds $*Wang Z, Islam MJ, Su R, Vukotic VN
17:40
NSERC CREATE Program in Continuous Flow Science *Kairouz V, Collins S, $Charette AB
17:40
Design of A Novel Chromene Family, A Combination of Biologically Active Molecules: Synthesis, Antimicrobial and Cytotoxic Behavior as well as SAR Study Assirey E, Alsaggaf AA, Okasha RM, Afifi TH, $*Abd-El-Aziz AS
17:40
Cu-based Sensitizers for Photoredox Reaction Clementine CM, $*Shawn SC
17:40
Gold-catalyzed Reactions in Microreactors $*Hashmi ASK, Bay S, Röder T, Baumeister T
17:40
Copper-catalyzed Iodovinylation of Hydrazides and Carbazates Casault PC, Daoust BD
17:40
Synthesis of 2,4-diacetamido-2,4,6-trideoxy-L-altrose: A Key Intermediate in the Synthesis of Pseudaminic Acid Sequeira CA, $Ling C-C
17:40
Synthesis of 1,2,4,3-Triazaphospholene Catalysts Tien CH, $*Speed AWH
17:40
Fast and Simple Access to Phosphindolium Salts $*Hashmi ASK, Arndt S
17:40
Alkynedicobalt Mediated Vinylogous Nazarov Reaction Almubayedh S, $Green JR
17:40
A "Radical" Access to Pentafluorosulfanyl- and Trifluoromethyl-containing Heterocycles Gilbert A, Desroches J, $Paquin J-F
17:40
Light Mediated Copper Catalysed C-C Bound Formation Grenier-Petel J-C, $Collins SK
17:40
Relative Stability of Hexacarbonyldicobalt Propargylic Carbocations - Effect of Remote Substitution St. Onge B, Penner P, Skieneh J, Adams S, $*Green JR
17:40
Linear and Cyclic Peptides as Green Catalysts for Chiral Epoxidations Bérubé C, Barbeau X, Laguë P, $*Voyer N
17:40
Cross-coupling of (Hetero)aryl Halides with Primary Amides Using (DiMeIHeptCl)Pd(cinammyl)Cl Precatalyst Sharif S, *Organ MG
17:40
Development of Aminosteroid Derivative Libraries by Solid-phase Synthesis to Identify New Anti-cancer Agents Dutour R, *Poirier D, $Maltais R, Perreault M, Roy J
17:40
Novel Photochromic bis(thienyl)ethene Based Crown Ethers for Preparation of Mechanically Interlocked Molecules Reynolds MR, *Baggi G, $Loeb SJ
17:40
3D Printable, Rapid Cure Silicone Elastomers Prepared Using Thiolene "Click" Chemistry Zheng SJ, *Brook MA
17:40
Synthesis of Cyclodextrin-based Oligomers with Different Cavity Sizes Zhang ZG, $Ling CC
17:40
Fast Solid-phase Synthesis of 17b-HSD10 Inhibitors as Potential Therapeutic Agents against Alzheimer's Disease Boutin S, *Poirier D, Maltais R, Roy J
17:40
Enantioselective Organocatalytic Michael/Aldol Sequence: Total Synthesis of the Anticancer Natural Product (+)-trans-Dihydrolycoricidine Zepeda-Velázquez C, $*McNulty J
17:40
Structure and Reactivity of 1,3-Bis(dimethylamino)-3- iodopropargyl Iodide Land MA, Robertson KN, *Clyburne JAC
17:40
Fluorescence and Catalysis by Cyclopropenium $*Dudding T, Mir R
17:40
gem-Difluoroination of Terminal Allenes Using (Difluoroiodo)toluene Zhao Z, *Murphy GK
17:40
Reduction of Benzhydrols with Diethyl Ether under Mild Acidic Conditions Cook AJ, $*Bolshan Y
17:40
Synthesis of Aza-bicyclic Frameworks by Sequential Intramolecular Vilsmeier-Haack and Organocatalyzed Mannich Reactions Outin J, $Bélanger G
17:40
Computational and Experimental Analysis of Anionic 5-exo/6-endo-dig Cyclization toward Pyrrolone and Pyridinone Infante G, $*Eisler S
17:40
Dibenzofurans and Pseudodepsidones from the Lichen Stereocaulon paschale Collected in Northern Quebec Carpentier C, Ferreira Queiroz E, Marcourt L, Wolfender J-L, Azelmat J, Grenier D, Boudreau S, Voyer N
17:40
Preparation and Reactivity of Bisaminocyclopenylidene (BAC) Carbene-borane Adducts Huchenski BSN, $*Speed A
17:40
Synthesis of Meta-substituted Phenols By Palladium-catalyzed C-C Bond Formation and Oxidation $*Orellana A, Wang Z, Samadi S
17:40
Aryl Ether Synthesis via ortho-Quinone / Phenol Cross-coupling Huang Z, $*Lumb J-P
17:40
Total Synthesis of the Potent Anticancer Agent Prunustatin A Chojnacka MW, $Batey RA
17:40
Synthesis of b-keto-a,a-difluorosulfonamides and Difluoromethanesulfonamides Soley JA, $Taylor SD
17:40
Late Stage Introduction of Quaternary Stereocentres: Towards the Synthesis of Puraquinonic Acid Elmehriki AH, $*Gleason JL
17:40
Restoring Chloroquine Efficacy and Determination of its Mechanism Kapuku B, $Bohle DS
17:40
Synthesis of Aminodiols by Enantioselective Haloamination Reactions *Papa BL, Vinhato E, $Rodrigues A
17:40
Chemo- and Stereoselective Rhodium-Catalyzed Ene-Cycloisomerization of Thioether-Substituted Alkenylidenecyclopropanes: Metal-Mediated b-Sulfide Migration Su Y, *Evans PA
17:40
Stereoselective Synthesis of a Highly Oxygenated d-Lactone Related to the Core Structure of (-)-Enterocin Wegmann M, *Bach T
17:40
Mild, Palladium-catalyzed Lateral Functionalization of Pyridines $*Orellana A, Rasheed F, Wasfy N
17:40
Studies towards the Total Synthesis of Geleganidine B Kerkovius JK, $Kerr MA
17:40
The Role of Lipoxygenase-catalyzed Lipid Peroxidation in Ferroptotic Cell Death Shah R, $Pratt DA
17:40
Supramolecular Enhancement of Photochromism in Mechanically Interlocked Molecules Baggi G, Loeb SJ
17:40
Intramolecular -Complexation in Transient Alkenyl- and Alkynylgermylenes $*Leigh WJ, Jeyakanthan K
17:40
Photoredox Transformations of Organic Halides Michelet B, Deldaele C, Kajouj S, Moucheron C, *Evano G
17:40
Synthesis of Carbazoles and Azahelicene Using Flow Chemistry Caron A, Hernandez-Perez AC, $*Collins SK
17:40
Visible Light Photocatalyst Reduction of a,b-Unsaturated Carbonyls: Utilisation of Radical Enolates $Simpson QJ, Hutt O, *Lupton DW
17:40
Three Component Coupling of Organoaluminums, Silylated Amines, and Aldehydes Tarasewicz A, Ensan D, $*Batey RA
17:40
Real Time Reaction Profiling by HPLC-MS Using a Prototype Automated Laboratory Toolkit Malig T, Koenig J, $*Hein JE
17:40
Key Bond Constructions in the Synthesis of Neomarchantin A Aided by Continuous Flow Methods Morin É, Raymond M, Dubart A, $*Collins SK
17:40
Unusually Stable Gold Nanoparticles Protected by Large Dithiol Ligands Salloum S, Zghal O, *Yu J, $Eichhorn SH
17:40
Phenoxazine-derived Antioxidants: The Ideal Compromise between Activity and Stability? Farmer LA, Haidasz EA, $*Pratt DA
17:40
Benzoxazine Derived Nitroxides and their Activity as Radical-trapping Antioxidants Harrison K, Haidasz E, $*Pratt D
17:40
A Mild and Non-oxidative Work-up for the Dioxaborolane-mediated Enantioselective Cyclopropanation with Enhanced Functional Group Compatibility Siddiqui SH, Navuluri C, *Charette AB
17:40
Synthesis and Utility of 4-Alkynals *Hearne ZL, Wang H, $Li C-J, Dalko M, Hitce J, Marat X, Moreau M
17:40
Synthesis of Alkynylphosphine Oxides and their Use in Intramolecular Carbolithiation Gérard P, Veillard R, Alayrac C, Gaumont A-C, *Evano G
17:40
One-pot Michael Addition, Oxidative C-H Insertion Reactions of N-Acryloyl Indole plus Application towards Total Synthesis of Tronocarpine Irwin LC, $Kerr MA
17:40
Ruthenium-catalyzed bis Homo Diels Alder [2+2+2] Cycloaddition Reactions between 1,5-Cyclooctadiene and Various Alkynes Petko D, Stratton M, $*Tam W
17:40
Copper-mediated Nucleophilic Addition/Cascade Cyclization of Aryl Diynes $Sinclair GS, Yang T, Wang S, Chen WH, *Schipper DJ
17:40
Photochemical Extrusion of Dinitrogen from Boryl Azides: Ligand-biased Intramolecular versus Intermolecular Boryl Nitrene Reactivity Atienza BJP, $*Williams FJ
17:40
Development and Reactivity of a New Class of Mesoionic 1,3-Dipole Erguven H, $Arndtsen BA
17:40
Multicomponent Covalent and Noncovalent Self-assembly in Salty Water Beatty M, Kim B, $Hof F
17:40
Green and Low Cost Synthesis of 3,3',5,5'-Azobenzene Tetracarboxylic Acid Salloum S, Albano N, Makawi E, $Eichhorn SH
17:40
Mechanism of Formation and Quantification of Lipid Derived Electrophiles $*Frenette M, Parent-Vézina S, Benoit A, Guillemette J-P
17:40
BODIPY Phos-faux-lipids: Synthesis of BODIPY Fatty Acids Bentley J, Lo K, Whelan L, $Koivisto B
17:40
Expedient Synthesis of Acyl Silanes from Silyl Acetylenes via the Meyer-Schuster Rearrangement $*Orellana A, Nikolaev A
17:40
Divergent Reactivity of N-Isocyanates with Primary and Secondary Amines: Access to Pyridazinones and Triazinones Derasp JS, Vincent-Rocan J-F, $*Beauchemin AM
17:40
A Catalytic Aerobic Approach to Xanthones by ortho-Quinone / Phenol Cross-dehydrogenative Coupling Huang H, $*Lumb J-P
17:40
The Mechanism(s) of Nitroxides as Catalytic Radical Trapping Antioxidants *Griesser M, Zilka O, Haidasz EA, $Pratt DA
17:40
Boronic Acid Catalysis: A Versatile Strategy for Carbon-carbon Bond Formation by Direct Functionalization of Alcohols Mo X, *Hall DG
17:40
Synthesis and Characterization of Prodigiosene F-BODIPYs Greening SM, $Thompon A
17:40
Base Catalyzed Substitution/Copper Catalyzed Cyclization of O-substituted Isocyanates: One Pot Synthesis of 1Alkoxy-benzimidazolones Wang Q, An J, Xiao WJ, *Beauchemin AM
17:40
Development of 3,5-di-tert-Butylphenol as a Model Substrate for Biomimetic Aerobic Copper Catalysis Kwon O, Esguerra KVN, Glazerman M, Petitjean L, Xu Y, Ottenwaelder X, $*Lumb J-P
17:40
Chiral b-Amino Sulfenates: Synthetic Access and Diastereoselective Alkylation Findlay JP, $*Schwan AL
17:40
Zn-mediated Synthesis of Cyclopropanated N-heterocycles from Cyclopropanols Lee JB, $Rousseaux S
17:40
Synthesis of New and Versatile Heterocyclic Chiral Allylic Boronates via Borylative Migration Chemistry Clement HA, *Hall DG
17:40
Synthesis and Characterisation of Dicyanotetraoxapentacene and Derivatives as New Discotic Mesogens Hiscock LK, Raycraft B, $*Maly KE
17:40
Highly Functionalized Building Blocks for the Synthesis of New pi-Conjugated Oligomers Fillmore BC, Eisler S
17:40
Pd-Catalyzed Spirocyclization via Carbopalladation, ortho-C-H Activation and Benzyne Insertion Yoon H, Lossouarn A, Landau F, $*Lautens M
17:40
Palladium-catalyzed Cross-coupling Reaction towards a Modular Synthesis of a Tunable Anion Receptor Messina C, Buonomano C, $*Forgione P
17:40
A Palladium Catalyzed Carbonylative C-H Functionalization of Arenes Kinney RG, Tjutrins J, Liu N, Kulkarni O, $*Arndtsen BA
17:40
Nickel Catalyzed C(sp3)-N Bond Formation Patel P, $Rousseaux S
17:40
Anthocyanin Derived Products for Use in Food Dyes Quilty AT, Wagner BD, McCallum JL, $*Kirby CW
17:40
A Palladium Catalyzed Route to b-Lactams via Aryl Halide Carbonylation Torres GM, De La Higuera Macias M, $*Arndtsen BA
17:40
Synthesis Of Clostridium Bolteae Capsular Polysaccharide Fragment: A Repeating Disaccharide Unit Davidson J, Stratton M, Gauthier-Signore C, Auzanneau FI
17:40
A New Plan for the Synthesis of Thiotetronic Acids Found in Groundwater Sing M, $*Schwan AL
17:40
The Homocoupling of Iodoarenes via Gold Photoredox Catalysis *Tran H, McCallum T, Morin M, $Barriault L
17:40
New Hydrogen Bonding Modes of Activaiton of Donor-acceptor Cyclopropanes Renwick CR, Irwin LC, $Kerr MA
17:40
The Synthesis of Novel Medium-sized Rings and Peptide Boronic Acids Using b-Amino Boronic Acid Building Blocks Soor HS, *Diaz DB, $Yudin AK
17:40
The Cytotoxicities of Primary and Secondary Products of Cholesterol Autoxidation *Schaefer EL, Zielinski ZAM, Shah R, $Pratt DA
17:40
Amphoteric Reagents in the Synthesis of Previously Inaccessible Boron-containing Heterocycles Holownia A, *Corless V, Diaz DB, Liew SK, $Yudin AK
17:40
(Aminomethyl)pyridine Complexes for the Cobalt-catalyzed Anti-Markovnikov Hydrosilylation of Alkoxy- or Siloxy(vinyl)silanes with Alkoxy- or Siloxyhydrosilanes $*Lee KL
17:40
The Cyclopropanol Minisci Reaction $*Orellana A, Nikolaev A, Zhang M
17:40
Quantifying the Reactivity of Phenolic Esters for Traceless Protein Labeling Sader J, $Menard F, *Kapras V
17:40
Azopeptide Strategy to Obtain Constrained Smac Mimetics that Induce Cell Death Chingle RM, *Lubell WD
17:40
Exploring BODIPY-phenylacetylene Rotaxanes as Artificial Photosynthetic Systems Sritharan S, *Yousaf M, $Koivisto B
17:40
Synthesis of alpha-Arylnitriles through a Nickel Catalyzed Cyanation Michel N, $Rousseaux S
17:40
Complex Derivatives of Catechol and 1,2-Benzoquinone: Redox and Associative Properties $Langis-Barsetti S, Lévesque A, Maris T, *Wuest JD
17:40
Enamine Additon to Silicon Compounds Promnitz CE, $*Zelisko PM
17:40
Cross-coupling of Hetero(aryl)Chlorides with Hindered Amines Using Pd-PEPPSI IPentCl Precatalyst and BHT Base Khadra A, *Organ MG
17:40
A Directed Metalation Group (DMG) Dance for the Regioselective Functionalization of Benzimidazoles Deichert JA, Hurst TE, Friedman A, Gomes S, Singh S, $*Snieckus V, Kitching MO
17:40
Gem-Difluorination of a-Diazo Amides Using (Difluoroiodo)toluene Tran R, $Murphy GK
17:40
Catalyst-controlled Selectivity in Alkylative Cross-couplings of Ester Electrophiles Masson-Makdissi J, $Newman SG
17:40
Synthesis of Highly Functionalized Benzo-fused 1,4-diazepin-3-ones and 1,5-diazocin-4-ones by Sequential Ugi and Intramolecular SNAr Reactions Vézina-Dawod S, Gerber N, Liang X, $*Biron E
17:40
Light Induced Dehalogenation of Halobenzene Using Carbon Quantum Dots Lemieux AJ, $Caputo CA
17:40
Efforts towards Enamine Catalyzed [3,3]-sigmatropic Rearrangements Vinet L, $*Drouin A
17:40
Total Synthesis of Thapsigargin *Chen DZ, $Evans PA
17:40
The Synthesis of Alkoxy-substituted bis(Phenyl Ethynyl)pentacene Derivatives as Potential Liquid Crystalline Materials Foroughian N, $*Maly KE
17:40
Diastereoselective Borocyclopropanation of Allylic Ethers and Styrenes *Benoit G, $Charette AB
17:40
Development of Stereoselective Methods for the Synthesis of Chiral b-Aminoalkylboronates Li X, $*Hall DG
17:40
New Perspectives for Lewis Acid Catalyzed [2+2] Cycloadditions between Alkenes and Allenoates Wiest JM, $*Brown MK
17:40
Azabicyclo[X.Y.0]Alkanone Peptidomimetic Synthesis Atmuri NDPa, $*Lubell W
17:40
Accounting for the Diverse Product Distribution in the Autoxidation of Cholesterol Zielinski ZAM, $Pratt DA
17:40
Phthalaldehyde Catalyzed Hydrolysis of Organophosphinic Amides and Related Derivatives Li BJ, Simard RD, *Beauchemin AM
17:40
A Bio-inspired Synthesis of Benzothiazines Halloran MW, Li E, Esguerra KV, Huang Z, $Lumb J-P
17:40
Improved Hydrochlorination Process for the Synthesis of a Chlorouridine Intermediate, en Route to Hepatitis C Treatment MK-3682 $*Zultanski SL, Hyde A, Limanto J, Moment A, Klapers A, Bernardoni F, Lee I, Waldman J, Lee A, Dunn R, Zhao R, Bachert D, Truong V, Zhao G, Nowak T, Mengel C, Ji Chen YN, Cohen R, Reibarkh M, Alvarado JM, Ruck R
17:40
Investigating Ring-opening Reactions of Cyclopropanated Oxabenzonorbornadienes Boutin R, Carlson E, $*Tam W
17:40
Synthesis of c,d-Unsaturated a-Aminoketones Using a Tandem Copper-catalyzed Vinylation Reaction Followed by a Claisen Rearrangement *Ricard S, Daoust B, $Gagnon A
17:40
Sulfoxidation of Alkenes and Alkynes with NFSI as a Radical Initiator and Selective Oxidant Zhang Y, Wong ZR, Wu X, Lauw SJL, Huang X, Webster RD, $*Chi YR
17:40
Construction of Stereogenic Quaternary Centers Using Photoredox Catalysis and Application to the Synthesis of Novel Nucleoside Analogues Lussier T, Waltz ME, $*Guindon Y
17:40
Hydrofluorination and Difluorination Reactions of Acetophenone Hydrazone Derivatives Using (Difluoroiodo)Toluene Carle M, $Murphy GK
17:40
Synthesis and Reactivity of a-Tosyloxy Boronic Esters Roest PC, $*Batey RA
17:40
A Highly Convergent Total Synthesis of Dolabriferol C (One-pot Stereoselective Bis-aldol Reactions) Diddi N, $*Ward DE
17:40
Synthesis of Novel Pentacene Derivatives with Fused Thiophene Rings as Potential Semiconducting Materials Antoniani A, Halloran M, $Maly K
17:40
Synthesis of Sulfur Containing Triphenylamine Based Dyes for Dye Sensitized Solar Cell Applications Simoes SA, $Koivisto BD
17:40
Synthesis of Substituted Trinaphthylenes and Tetranaphthylenes via Yamamoto Coupling Bellemore VM, $Maly KE
17:40
Development of an Asymmetric Organocatalytic [2+2] for the Synthesis of Tetrasubstituted Heterodimeric and Homochiral Cyclobutanes *Nielsen AJ, Jenkins HA, $McNulty J
17:40
Oxazolium Salts as NHC Pre-catalysts Garapati VKR, $*Gravel M
17:40
Synthesis of Allenyl Sulfenates and an Investigation of their Reactivity Michalski MM, Kulak MR, Hirst M, $*Schwan AL
17:40
A Nickel-catalyzed Oxa-Heck Reaction Vandavasi JK, *Hua XY, $Newman SG
17:40
Palladium-catalyzed Ring-opening Reactions of Cyclopropanated 7-Oxabenzonorbornadiene with Alcohols Tait K, Boutin R, Alrifai O, $*Tam W
17:40
A New Brønsted Acid-catalyzed Dual-natured Coupling Reaction Harris DH, *Bolshan Y
17:40
Sequestering n-Alkanes in a Perfluoroindazole Based Non-covalent Organic Framework Mailman A, Peuronen A, Lahtinen M, $*Tuononen HM
17:40
Biomimetic Cu-catalyzed Aerobic Oxidation of Phenols: Ligand Design and Substrate Effects Kwon O, Xu Y, Solano LAR, Esguerra KVN, Ottenwaelder X, $*Lumb J-P
17:40
Computational Investigation of Thionitrate Decomposition Pathways and the Reactivity of the GAPDH Enzyme Parmar V, Orabi E, English AM, $*Peslherbe GH
17:40
Synthesis of Non-nucleoside Antiviral Cyclopropylcarboxacyl Hydrazones and Initial anti HSV-1 Structure-activity Relations *Dokuburra CB, $McNulty J, DAiuto L, McLain L, Piazza P, Williamson K, Nimgaonkar VL
17:40
Novel Trialkylphosphoranylides for the Two-carbon Homologation of Aldehydes to a,b Unsaturated Aldehydes *McLeod D, $McNulty J
17:40
Synthesis and Biological Activity of Natural Quinones, Resorcinols, and their Derivatives $*Sisa M, Vanek T
17:40
New Synthetic Approaches to Halichondrin B Related Drug Substances $*Rudolph A
17:40
Design and Synthesis of Ligand-directed Fluorescence Probes to Track Kainate Receptors in Living Cells Tian Z, *Menard F
Thursday AM
OR3
206F
Reactivity in Organic and Biological Chemistry - joint with BM
Organizer(s) - Jason Hein, Ronald Kluger
Chair(s) - Jason Hein
08:00
Characterization of Glucose 6-Phosphate 3-Dehydrogenase, an Unusual Enzyme with an Unusual Product Vetter ND, $*Palmer DRJ
08:20
Reactivity at the Active Site of Mandelate Racemase $*Bearne SL, Douglas C, Nagar M, Aboushawareb S
08:40
Mimicking and Modifying Lipid Membranes Using Chemoselective Reactions $*Devaraj NK
09:20
New Chemistry from the Sea: Enzymatic Cleavage of Phosphonate CP Bonds via CH Bond Activation $*Zechel DL
09:40
Biosynthesis in Marine Proteobacteria, Unusual or just Underexplored? $Ross AC
10:00
 
Coffee Break
10:20
Using Mechanistic Tools to Solve a Phosphorus Stereochemistry Challenge Ruck RT
11:00
On the Role of Lipid Peroxidation in Ferroptotic Cell Death $*Pratt DA
11:40
Why an Enolate Is the Key Intermediate in the Fragmentation and Rearrangement of a Prototypical Breslow Intermediate Bielecki M, $*Kluger R
12:00
 
End of Session
ORG1
206B
General Session 1
Organizer(s) - Eric Fillion
Chair(s) - Eric Fillion
08:00
Rhodium-catalyzed Enantioselective Isomerization of meso-Oxabenzonorbornadienes to 1,2-Naphthalene Oxides Yen A, Choo K-L, Yazdi SK, Franke PT, Webster R, Franzoni I, Loh CCj, Poblador-Bahamonde A, $*Lautens M
08:20
Sulfones as Versatile Electrophiles in Csp3 Suzuki-Miyaura Cross-coupling Reactions Ariki ZT, Rygus JPG, Nambo M, $Crudden CM
08:40
Enantioselective Rhodium-catalyzed Allylic Alkylation of Aldehyde Enolates $Wright TB, *Evans PA
09:00
Development of a Visible-light-mediated Synthesis of Alkynyl Sulfides Santandrea J, Minozzi C, Cruché C, $*Collins SK
09:20
Organic Transformations Using Photoredox Gold Catalysis McCallum T, $*Barriault L
09:40
Mechanistic Insights in Iridium/Nickel Co-catalyzed Photoredox Cross-coupling Reactions Juneau A, Mesko M, Oderinde M, $Frenette M
10:00
 
Coffee Break
10:20
Methodology Development of the Pd-catalyzed Hydrohalogenation of 1,6-Enynes Petrone DA, Franzoni I, Ye J, Rodríguez JF, $*Lautens M, Poblador-Bahamonde AI
10:40
Highly Efficient Diradical Cobalt(III) Catalyst for the Cycloisomerization of Alkynoic Acids *Leconte N, du Moulinet d'Hardemare A, Philouze C, Thomas F
11:00
Differential Functionalization of Carbohydrate Hydroxyls through Boronic Ester Intermediates Mancini RS, $*Taylor MS
11:20
Decarboxylative Oxidative Arylation of Phenylacetic Acid Derivatives with Aryl Boron Reagents Moon PJ, $Lundgren RJ
11:40
Hydrosilanes as Coupling Reagents for Amide Bond Formation Sayes M, Charette A
12:00
 
End of Session
ORG2
201C
General Session 2
Organizer(s) - Eric Fillion
Chair(s) - Wenjie Shao
08:00
Pyrene as a Platform for Donor-acceptor Oligoarylenes Walsh JC, Hogan DT, $*Bodwell GJ
08:20
Novel Synthesis of Heterocyclics Containing a Benzoquinone or Benzoquinoneimine Ring $*Odens HH
08:40
Simple Syntheses of Complex p-Systems by Condensations of Quinones Gueorguiev NP, Maris T, Wuest JD
09:00
Furan-Maleimide exo-Adducts: A Versatile and Highly Selective Dienophile for Polymerizations and Click Reactions St. Amant AH, $Read de Alaniz J
09:20
Enantioselective Diazepane Carboxylate Catalyzed Diels-Alder of Branched a,b-Unsaturated Aldehydes Häggman NO, Kaldre D, Zank B, $*Gleason JL
09:40
The Synthesis of Biostable Acetal-free TF Antigens Sadraei S, Desai A, Yousif G, $*Trant JF
10:00
 
Coffee Break
10:20
New Reactivity of Donor-acceptor Cyclopropanes Piotrowski ML, $Kerr MA
10:40
Total Synthesis of 6-deoxy-b-D-ido-heptopyranosides Related to Campylobacter jejuni Zhang P, Hevey R, $*Ling C-C
11:00
Efficient and Selective Palladium-catalyzed Telomerization of 1,3-butadiene with Carbon Dioxide Sharif M, Jackstell R, Al-Shihi B, *Dastgir S, Beller M
11:20
Hydropersulfides: H-atom Transfer Agents par Excellence Chauvin JPR, Griesser M, $*Pratt DA
11:40
Enol Ethers as Carbonyl Surrogates in a Modified Povarov Synthesis of Antiparasitic 3-Aryl Quinolines *Brown CE, Bordon C, Yolken R, Jones-Brando L, $McNulty J
12:00
 
End of Session
Thursday PM
OR3
206F
Reactivity in Organic and Biological Chemistry - joint with BM
Organizer(s) - Jason Hein, Ronald Kluger
Chair(s) - Ronald Kluger
13:40
Metal-free E-H bond Functionalization: From Concept to Applications $*Fontaine F-G, Misal L, Jayaraman A, Bura T, Rochette É, Légaré-Lavergne J, Bouchard N, Courtemanche M-A, Légaré M-A, Boutin H
14:00
2-Formylphenylboronate, a Potent Inhibitor of Mandelate Racemase Douglas CD, $*Bearne SL
14:20
Chemoselective Fluorescence Imaging of Nucleophiles, ROS and Redox Processes: From High Throughput to Single Particle to Single Molecule Events $*Cosa G
15:00
 
Coffee Break
15:20
Maleimide-based Protein Labelling $*Keillor JW
15:40
Engineered Aminotransferases for the Production of D-phenylalanine Derivatives Using Biocatalytic Cascade Reactions *Walton CJW, Parmeggiani F, Barber JEB, McCann JL, Turner NJ, $Chica RA
16:00
Host-guest and Bioconjugation Strategies Applied to Multisubunit Proteins and Bacteriophage $*Honek JF
16:20
Design of a 2nd Generation Boronate System for Rapid and Irreversible Bioorthogonal Conjugation Akgun B, Guzman VT, Derda R, $Hall DG
16:40
 
End of Session
ORG1
206B
General Session 1
Organizer(s) - Eric Fillion
Chair(s) - Eric Fillion
13:40
Application of Phase Separation Strategy and Continuous Flow Chemistry for the Synthesis of Complex Macrocycles Godin E, $*Collins SK
14:00
Access to 3-substituted Indoles Using Flow Chemistry Crifar C, *Lubell WD
14:20
Teaching Existing Technologies New Tricks in Continuous Flow Systems Lummiss JAM, Hicklin RW, Morse PD, $*Jamison TF
14:40
Reactivity Inversion of Cyclopropanols for the Synthesis of Cyclopropylamines Using Zinc(II) Salts Mills R, Barrera-Arbelaez L, Daponte J, $*Rousseaux S
15:00
 
Coffee Break
15:20
Oxalyl Boronates Enable Modular Synthesis of Bioactive Imidazoles Lee CF, Holownia A, Bennett JM, Elkins JM, $*Yudin AK
15:40
Ferrocenium Boronic Acid Catalysed Coupling of Alcohols with Alkenyl and Alkynyl Trifluoroborates Blackner JJ, $*McCubbin JA
16:00
Total Synthesis of Isoxeniolide A Betschart L, $*Altmann K-H
16:20
Biomass Furan Derivatives as Building Blocks for Organic Synthesis: Application of Decarboxylative Cross-coupling Methodologies Chacon-Huete F, $*Forgione P
16:40
 
End of Session
ORG2
201C
General Session 2
Organizer(s) - Eric Fillion
Chair(s) - Graham Murphy
13:40
The Stereoselective Cyclization of 1-Alkenyl b-Aminoalkyl Sulfoxides and Sulfones: Thiomorpholine S-Oxides with Three Chiral Atoms in the Ring $*Schwan AL, Soderman SC, Kulak MR, Mook T, Mawhinney RC, Gagnon KM
14:00
Studies and Applications of Intramolecular (4+3) Cycloadditions of Pyrroles *Chiu P, He J
14:20
Cyclopropenium Based Catalysis Mir R, $*Dudding T
15:00
 
Coffee Break
15:20
Rationale Design of Cytoprotective Agents Inspired by the Liproxstatins Faudot dit Bel P, Shah R, Zilka O, $*Pratt DA
15:40
Synthesis and SAR of Veranamine $*Magolan J, Araujo HC, Holmbo SD, Zhang X
16:00
Imide Functionality Enables Facile Synthesis of Medium-sized Cyclic Peptides Corless VB, Mendoza-Sanchez R, Nguyen NN, Frost J, Adachi S, Tantillo DJ, Yudin AK
16:20
A New Metalation Route to 2-Naphthols from Coumarin-2-ones: Application toward the Total Synthesis of Isoprekinamycin Patel J, Hurst T, $*Snieckus V
16:40
 
End of Session